Bacterial diversity in intestinal mucosa of antibiotic-associated diarrhea mice

Mucosa-Associated Bacterial Diversity in Necrotizing Enterocolitis

BACKGROUND Previous studies of infant fecal samples have failed to clarify the role of gut bacteria in the pathogenesis of NEC. We sought to characterize bacterial communities within intestinal tissue resected from infants with and without NEC. METHODS 26 intestinal samples were resected from 19 infants, including 16 NEC samples and 10 non-NEC samples. Bacterial 16S rRNA gene sequences were a...

Diversity of bacterial lactase genes in intestinal contents of mice with antibiotics-induced diarrhea

AIM To investigate the diversity of bacterial lactase genes in the intestinal contents of mice with antibiotics-induced diarrhea. METHODS Following 2 d of adaptive feeding, 12 specific pathogen-free Kunming mice were randomly divided into the control group and model group. The mouse model of antibiotics-induced diarrhea was established by gastric perfusion with mixed antibiotics (23.33 mL·kg-...

Update on Small Intestinal Bacterial Overgrowth and Antibiotic-responsive Diarrhea

Human intestinal microbiota gene risk factors for antibiotic-associated diarrhea: perspectives for prevention. Risk factors for antibiotic-associated diarrhea

28 Antibiotic-associated diarrhea (AAD) is associated with altered intestinal microflora and other 29 symptoms that may lead to possibly death. In critically ill patients, diarrhea increases rates of 30 morbimortality. Assessing diarrhea risks is thus important for clinicians. For this reason, we 31 conducted a hypothesis-generating study focused on antibiotic-associated diarrhea (AAD) to 32 pr...

Antibiotic associated diarrhea in children.

CONTEXT Keeping in view the recent flooding of the Indian market with antibiotic and probiotic combinations, we decided to look at the prevalence of antibiotic associated diarrhea (AAD) and Clostridium difficile infection (CDI) in children and reviewed evidence available for use of probiotics in the prevention of AAD. EVIDENCE ACQUISITION We did a PubMed, Medline and Cochrane libary search fo...